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应万涛,博士,副研究员1998年毕业于国防科技大学, 2004年放射与辐射医学研究所博士毕业并留所工作。2008.12009.12于美国波士顿大学医学院质谱中心/心血管蛋白质组学研究中心开展博士后研究。2010年回国就职于北京蛋白质组研究中心。先后以第一作者、通讯作者或共同作者发表SCI收录论文40余篇,参与编写蛋白质组研究相关专著7部。2007年国际人类蛋白质组组织大会上(HUPO)被授予亚太地区青年科学家奖。主持国家“973“课题一项,完成国家自然科学基金青年课题1项,并参与和完成国家863项目、973项目、国家科技攻关重大专项等多项课题。

主要研究方向为蛋白质组学及蛋白质翻译后修饰。研究重点为定量蛋白质组研究技术在疾病标志物发现研究中应用;糖基化蛋白质组学研究技术的开发,规模化糖蛋白质定性及定量表达谱建立,糖基化生物标志物发掘及糖基化修饰的调控机制探索。

与申请项目相关的代表性论文:

  1. Xin Liu, Jiyang Zhang, Zhaobin Zheng, Xing Yang, Wei Jia, Lei Li, Yan Gong, Yun Cai, Yunping Zhu, Fuchu He, Wantao Ying (Co-correspondence), Xiaohong Qian. A systematic N-terminal peptide quantitative labeling strategy for differential proteomic analysis. Proteomics-Clinical Application, 2010. Published Online: 9 Mar 2010
  2. Chinese Human Liver Proteome Profiling Consortium. First insight into the human liver proteome from PROTEOME (SKY)-LIVER(Hu) 1.0, a publicly available database. J Proteome Res. 2010, 9(1):79-94. (Co-first author)
  3. Jia W, Lu Z, Fu Y, Wang HP, Wang LH, Chi H, Yuan ZF, Zheng ZB, Song LN, Han HH, Liang YM, Wang JL, Cai Y, Zhang YK, Deng YL, Ying WT (Co-correspondence), He SM, Qian XH. A strategy for precise and large scale identification of core fucosylated glycoproteins. Mol Cell Proteomics. 2009, 8(5):913-23.
  4. Ying W, Perlman DH, Li L, Théberge R, Costello CE, McComb ME. Highly efficient and selective enrichment of peptide subsets combining fluorous chemistry with reversed-phase chromatography. Rapid Commun Mass Spectrom. 2009, 23(24): 4019-30.
  5. Ying W, Jiang Y, Guo L, Hao Y, Zhang Y, Wu S, Zhong F, Wang J, Shi R, Li D, Wan P, Li X, Wei H, Li J, Wang Z, Xue X, Cai Y, Zhu Y, Qian X, He F. A dataset of human fetal liver proteome identified by subcellular fractionation and multiple protein separation and identification technology, Mol Cell Proteomics. 2006, 5:1703-1707
  6. Chen M, Ying W (Co-correspondence), Song Y, Liu X, Yang B, Wu S, Jiang Y, Cai Y, He F, Qian X. Analysis of human liver proteome using replicate shotgun strategy. Proteomics. 2007 Jul;7(14):2479-88.
  7. Ying W, Jiang Y, Guo L, et al. A dataset of human fetal liver proteome identified by subcellular fractionation and multiple protein separation and identification technology, Mol Cell Proteomics. 2006, 5:1703-1707.
  8. Xiao T*, Ying W*, Li L, Hu Z et al. An Approach to Studying Lung Cancer-related Proteins in Human Blood. Mol Cell Proteomics. 2005, 4(10): 1480-6 (* equal contribution).
  9. Ying W, Hao Y, Zhang Y et al. Proteomic analysis on structural proteins of SARS coronavirus. Proteomics, 2004, 4(2): 492-504.
  10. Ying W, Zhang K, Qian X, et al. Proteome analysis on an early transformed human bronchial epithelial cell line, BEP2D, after a-particle irradiation. Proteomics. 2003, 3(1): 64-72.

 

联系方式:

 

蛋白质组学国家重点实验室,北京蛋白质组研究中心,北京放射医学研究所

 

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